Coenzyme Q10, commonly known as CoQ10 or ubiquinol, has gained popularity as a dietary supplement, especially for enhancing cardiovascular health. But what exactly is CoQ10, and how can it support our well-being? In this article, we’ll delve into the science behind CoQ10 and examine whether it deserves a place in your heart-healthy routine.

What is CoQ10?

CoQ10 is a naturally occurring substance found in all cells of the body, with the highest concentrations in vital organs like the heart, liver, kidneys, and pancreas (2). It plays a pivotal role in energy production, acting as a spark plug for our cellular engines. Additionally, CoQ10 possesses potent antioxidant properties, combating harmful free radicals that may contribute to cell damage and disease.

CoQ10 and Heart Health

Several studies suggest that CoQ10 may offer various benefits to the cardiovascular system:

1. Heart Failure: Research indicates that CoQ10 supplementation can enhance exercise capacity and improve the quality of life for individuals diagnosed with heart failure, attributed to improved energy production and antioxidant activity found in CoQ10 (2).

2. High Blood Pressure/Hypertension: Studies propose that CoQ10 may provide a modest reduction in systolic blood pressure, particularly for those with uncontrolled hypertension (3).

3. Statin Side Effects: CoQ10 may help alleviate muscle aches and fatigue, common side effects of statin drugs used to lower cholesterol.

4. Recovery after Heart Surgery: Preliminary evidence suggests that CoQ10 supplementation before and after heart surgery may improve heart function and reduce the risk of complications.

If you’re considering incorporating CoQ10 into your routine, consult your naturopathic provider at Peninsula Integrative Medicine. Dosage, form, and quality are important considerations, with recommended doses ranging between 100-300mg per day with food. Natural sources of CoQ10 include organ meats and cold-water fish like salmon, mackerel, anchovies, sardines, and herring (SMASH).

Lastly, we want to emphasize that good nutrition, regular exercise, and stress management create an important foundation in supporting overall cardiovascular wellness. The providers at Peninsula Integrative Medicine are ready to guide you in developing customized treatment plans and also help you determine if CoQ10 should be part of your daily regime!

1. Greenberg S, Frishman WH. Co-enzyme Q10: a new drug for cardiovascular disease. J Clin Pharmacol 1990;30:596-608
2. Molyneux, S. L., et al. Coenzyme Q10: an independent predictor of mortality in chronic heart failure. J Am Coll.Cardiol. 10-28-2008;52(18):1435-1441
3. Zhao D, Liang Y, Dai S, et al. Dose-response effect of coenzyme Q10 supplementation on blood pressure among patients with cardiometabolic disorders: A GRADE-assessed systematic review and meta-analysis of randomized controlled trials. Adv Nutr 2022